Flexuron®: A Revolutionary Step Forward in Joint Comfort

Rolling over to get out of bed… Wrapping your hand around a door knob… Taking the dog for a walk… Riding your bike… Gardening… Getting down on the floor to play with the kids…

For millions of people, these are everyday activities that they do without much thought—and without having to deal with joint health. But for millions of other people, they are a struggle—a chore because their joints aren’t as young as they used to be. And if you are one of the many adults who report joint health issues in national surveys then you know what it is like to skip something you enjoy because your joints made you put on the brakes.1
There are many reasons why a person could be having trouble with their joints but aging and injury are the most prevalent. And while we can do our best to avoid injury and still end up getting injured anyway, there is no known way to avoid aging. However, there are some things you can do for your joints that can help mitigate the effects of normal aging or make dealing with the after-effects of an injury a bit easier: see your doctor, rest, exercise, lose weight, use heat or cold, and take Flexuron®, a new nutritional supplement that out-performed glucosamine-chondroitin for promoting optimal joint comfort in clinical trials.*†

6 Tips for Taking Care of Your Joints

1. See Your Doctor: Your doctor should always be the point-person for your joint health care. Injuries should be attended to as soon as possible. And your doctor can help guide you through a healthy aging routine tailored to your specific needs.

2. Rest: Sounds simple, right? But let’s face it, getting proper rest can be difficult in today’s fast-paced, demanding world. But your joints need proper rest every day if they are to avoid being over-taxed.

3. Exercise: Counter-intuitive, but just as important as getting proper rest for your joints. Joints are a “use-it-or-lose-it” part of your body, as reported by a study in the Annals of the Rheumatic Diseases, which observed that if you don’t use your joints, the cartilage covering them tends to get thinner.2 And a second study published in the journal Arthritis and Rheumatism showed that moderate exercise can increase the thickness of joint cartilage and improve joint performance.3 So use your joints—but use them properly (which is where Tip #1 – See Your Doctor – comes into play again).

4. Lose Weight: Weight can be a sensitive topic, but your joints are sensitive to weight. Multiple studies have shown the relationship between body weight and joint discomfort, with one reporting that “being only 10 pounds overweight increases the force on the knee by 30-60 pounds with each step.”4

5. Use Heat… Or Cold: It can be confusing whether to use heat or cold on your joints. Sometimes the answer is one or the other, and sometimes the answer is both (though not at the same time).

Heat is good for soothing stiff joints because it enhances circulation and delivers nutrients to the joints and surrounding muscles. 5 Some people prefer heating pads while others like using moist heat packs. Whichever you use, follow the instructions on the device and do not use it for more than 20-minutes at a time.

Cold, on the other hand, is used for reducing swelling and inflammation because it restricts blood flow to the area and numbs the nerve endings. However, whether you use a frozen bag of peas or an ice pack, do not apply cold for more than 20-minutes.5

6. Use Flexuron®: Getting proper nutrition to your joints can be key to improving their comfort, flexibility, and mobility. Flexuron® is a patented combination of three key nutrients for joint health: omega-3 from krill oil, antioxidant-rich astaxanthin, and hyaluronic acid, which is a component of your joint’s lubricating synovial fluid.*

When people in the past thought about joint comfort supplements, glucosamine-chondroitin is what most readily came to mind. However, Flexuron® will change that. In a double-blind, placebo-controlled clinical study, the Flexuron® formula performed on average 3-to-5-times better that glucosamine-chondroitin as reported by test subjects using the WOMAC Pain Score Scale (The Western Ontario and McMaster Universities Arthritis Index, a widely used set of protocols for assessing pain).† Study participants reported improved joint comfort in as little as 7 days, with increasing improvement over the course of 56 days when measured on the VAS Scale (the Visual Analog Scale, which measures subjective attitudes).

It’s the special combination of ingredients in Flexuron® that make the difference:

PhosphoBoost™ Krill Oil is a great source of Omega-3, and the phospholipids version used in Flexuron® carries the EPA & DHA components of Omega-3 directly into your cells, promoting absorption.* A meta-analysis of studies on Omega-3 concluded that supplementation can improve joint comfort.6

The molecular structure of Astaxanthin gives it an exceptional ability as an antioxidant to help fight joint damage caused by free radical oxidative stress.* Astaxanthin is also valued for a number of other stellar benefits including muscle endurance and circulation, both of which can play a role in joint health.*

Low Molecular Weight Hyaluronic Acid serves as a building block for healthy joints and skin.* This gel-like substance is the joint matrix’s “shock absorber,” making it a key component of joint health and comfort.* Unfortunately, the body’s own hyaluronic acid level begins to decline as we age. Supplementing with Flexuron® can help replace some of what the body has lost.*

Put It All Together For Healthy Joints

Your joints support you, so it’s only natural that you will want to support them. Achy joints are never fun; they can slow you down and even keep you from doing the things you enjoy. But with proper care — doctor visits, rest, exercise, weight loss, heat/cold, and Flexuron® — you can increase your joint comfort and flexibility and improve your mobility.* Try something new today to give your joints a helping hand and your joints will give you a standing ovation!

1 – https://www.webmd.com/pain-management/guide/joint-pain#1. Accessed June 2018.

2 – Eckstein F, Lemberger B, Gratzke C, Hudelmaier M, Glaser C, Englmeier KH, Reiser M. In vivo cartilage deformation after different types of activity and its dependence on physical training status. Ann Rheum Dis 2005;64:291-295.

3 – Roos EM, Dahlberg L. Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: A four-month, randomized, controlled trial in patients at risk of osteoarthritis. Arthritis Rheum 2005;52:3507-3514.

4 – Role of Body Weight in Osteoarthritis. https://www.hopkinsarthritis.org/patient-corner/disease-management/role-of-body-weight-in-osteoarthritis/. Accessed June 2018.

5 – Using Heat and Cold for Pain Relief. https://www.arthritis.org/living-with-arthritis/treatments/natural/other-therapies/heat-cold-pain-relief.php. Accessed June 2018.

6 – A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. RJ Goldberg and J Katz. https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0024571/. Accessed June 2018.

† – 3 to 5 Times Better than Glucosamine and Chondroitin at Promoting Total and Maximum Joint Comfort as measured in Clinical study (improvement in WOMAC Pain Scores after subtracting out the placebo response).

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Feed Your Brain with Astaxanthin

Astaxanthin may not be a familiar name, although you consume a little any time you eat salmon. Astaxanthin is a carotene – carotenes are natural pigments, similar in molecular structure to the more familiar beta carotene that colors carrots and other vegetables and fruits. Astaxanthin gives salmon its distinctive reddish hue, but it does much more: astaxanthin works as powerful antioxidant in plant and animal cells, which translates into a broad range of beneficial effects on cellular function. Astaxanthin, as shown in a growing body of research studies, published in peer-reviewed scientific journals, is even more potent and versatile than its carotene cousins.

Like beta carotene, astaxanthin is good for the eyes, the skin and other tissues where antioxidants are needed. Recent studies point to astaxanthin as a nutrient for the brain. An in-vitro (test-tube) study reported to the International Congress of Nutrition and published in the journal Forum of Nutrition, SH-SY5Y cells, which are used in experimental models of neuron function, were bathed in astaxanthin and then exposed to chemicals that cause “oxidative stress” in cells. (Antioxidants are substances that counter oxidative stress in biological systems, hence the term “antioxidant.”) Astaxanthin successfully protected the treated cells from damage. Based on this, and previous research showing that astaxanthin is capable of crossing over from the bloodstream into the brain, the report suggests that “pre-treatment with astaxanthin may be effective for oxidative-stress associated neurodegeneration and a potential candidate for natural brain food.

High quality natural Astaxanthin from Haematococcus pluvialis, grown under controlled conditions to ensure purity and safety, is available as a supplement in the US.

Liu X, Osawa T. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food. Forum Nutr. 2009;61:129-35.

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Astaxanthin, the “Natural Brain Food” That Benefits Cognitive Function

In a previous Research Spotlight, we summarized research showing that astaxanthin—the beta-carotene-like natural pigment that makes salmon red—protects brain cells from damage by toxic free radicals, a biological phenomenon known as “oxidative stress.” Astaxanthin is described in a report published in Forum of Nutrition as “a potential candidate for natural brain food.”

While inhibition of oxidative stress in brains cells is important enough by itself, does the protective effect make any difference in thinking? A placebo-controlled, double-blind study, reported in the Journal of Clinical Biochemistry and Nutrition — a peer-reviewed scientific publication—found evidence that it does. Ninety-six heathy middle-aged and elderly people who experienced the kind of mild forgetfulness that commonly occurs with aging were recruited to participate in this research. The volunteers took astaxanthin, extracted from Haematococcus pluvialis, an algae naturally-rich in astaxanthin, or a placebo (“dummy pill”) daily for 12 weeks. Two modest doses of astaxanthin were used: 12 mg in the “high-dose group” and 6 mg in the “low-dose group.” Tests of cognitive function were administered to all subjects every four weeks. Improvements were seen in both dosage groups at the end of the 12-week study period. Interestingly, the low-dose group raised their scores earlier than the high-dose group in one of the tests:the Groton Maze Learning Test. The sample-size, i.e. the number of subjects, was too small for the data to reach “statistical significance,” nonetheless the report concludes that “the results suggested that astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.” No side-effects occurred; astaxanthin, like other carotenes, is completely safe as nutritional supplement that can be taken on a daily basis.

High quality natural Astaxanthin from Haematococcus pluvialis, grown under controlled conditions to ensure purity and safety, is available as a supplement in the US.

Liu X, Osawa T. Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food. Forum Nutr. 2009;61:129-35.

Katagiri M, et al. Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomised, double-blind, placebo-controlled study. J Clin Biochem Nutr 51(2):102-7.

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Protect Your Skin from the Sun with Astaxanthin

Astaxanthin is a natural pigment belonging to the class of nutrients known as carotenes. Similar to beta-carotene, the more familiar carotene that makes carrots orange, astaxanthin produces the reddish-orange color of salmon. (Ocean-growing salmon get their astaxanthin by eating Krill, a tiny shrimp-like crustacean.) Like beta carotene and other members of the carotene family, astaxanthin is a powerful antioxidant—this biological property works at the cell level to protect a diverse range of tissues from “oxidative stress”, an ongoing metabolic process in the body that can be damaging if not kept under control. Astaxanthin is now one of the most popular ingredients in dietary supplements—thanks to a wealth of research exploring its many health benefits.

Carotenes are good for skin, and astaxanthin is no exception. As the body’s most external tissue, the skin is vulnerable to rogue molecules called “free radicals” that can accumulate in tissues on the heels of a surge in oxidative stress. Ultraviolet light (UV) exposure subjects the skin to oxidative stress and accumulation of free radicals that contributes to skin damage and aging. In view of this, a study was undertaken to investigate the ability of astaxanthin and other carotenes to mitigate the effects of UVA light on fibroblasts in the dermis. Fibroblasts, cells that are abundant in connective tissues like skin, build collagen and other structural components. The experiments, published in the scientific journal Experimental Dermatology, demonstrated a “photoprotective effect” of carotenes on dermal fibroblasts. Astaxathin was a stand-out: as stated in the report, “The data indicated that the oxo-carotenoid astaxanthin has a superior preventative effects towards photo-oxidative changes in cells culture.”

Emanuela C, et al. Astaxanthin, canthaxanthin and ß-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-response enzymes. Exp Dermatol 2009;18:222-31.

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AstaFX Astaxanthin Super Formula

Our AstaFX Astaxanthin Super Formula has becoming very popular!

AstaFX™ doesn’t just contain Astaxanthin; it exclusively blends AstaREAL®, an evidence-based Astaxanthin backed by multiple studies and patents with Organic Flax Oil. Clinical studies document the ability of AstaREAL® to naturally support: healthy energy levels, healthy skin, visual acuity, muscle endurance and recovery, immunity and circulation.*

*These statements have not been evaluated by the Food and Drug Administration.

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